Prevention or resolution of microbial colonization of wounds is critical to rapid and uneventful healing. The use and misuse of anti-microbial agents continues to support the evolution of multi-drug resistant organisms that can cause severe or life-threatening infections. Silvacide™ is a revolutionary development in the arsenal of antimicrobial weapons. Silvacide™ on its own is a powerful, broad spectrum antibacterial and antifungal agent with the added benefit that its method of acting on bacterium inhibits their ability to develop resistance. In addition, Silvacide has been shown to potentiate the effects of antimicrobial compounds in vitro as well as reducing the probability that pathogens will develop resistance to the antimicrobials and substantially reduces the amount of antimicrobials needed to kill bacteria and fungi.

It is well known that we face a near crisis in the battle against pathogenic microbes. The rise in MRSA's to an average of 10% is evidence that we are losing the battle. Research shows that this condition is the result of bacteria's adaptive ability to rapidly adjust it's defenses to combat new drugs, thus becoming resistant to their effects. New strains quickly evolve strategies to defend themselves in two main ways. First, they keep destructive antibiotics at bay by altering the biofilm, or defense shield, that they quickly product upon colonization. The biofilm acts both as a protective shield and to capture nutrients. The nutrients pass easily through to nourish the growing colony, while hazardous materials (antibiotics) are prevented from reaching the bacteria and doing their work. The second protective mechanism results from an intelligent membrane, the external structure of the bacteria.

The cell wall "reads" substances coming in contact with it and if it 'senses' a potentially harmful substance it quickly rejects this substance before it can enter the interior where most antibiotics are designed to do their work. When it encounters a new antibiotic that has not yet been registered as harmful it allows this substance to pass. The bacteria is then destroyed, however some bacteria manage to avoid accepting a new antibiotic because of a random quirk in their 'hazardous substance registry' and all of their offspring retain their accidental resistance. Future generations easily avoid the destructive antibiotic.

How does Silvacide™ manage to defeat the bacteria's defense mechanism? It is really quite simple. Silvacide™ creates an ionic instability in both the microbe's membrane as well as the secreted biofilm. The ionic instability generates openings, or holes, in the membrane or biofilms, thereby effectively bypassing the microbe's principle defense mechanisms and allowing entry of antimicrobial agents. Although Silvacide™ carries an effective antimicrobial concentration of ionic silver (40 micrograms/ml), additional antimicrobial agents may be combines with Silvacide™. When combines with Silvacide™ even Penicillin becomes effective against drug resistant bacteria.

Not only does Silvacide™ serve as a powerful antibacterial agent, but it is also effective against fungal infections including Candida albicans, Fusarium sp., Aspergillus niger and Microsporum Gypseum.

 

 

Vital Ionics, Inc. is an Advanced Wound Care Products Distributor. We service customers throughout Florida, and we service customers Nationwide.